News
Thoughts on discovery, milestones from the company, and the papers behind our science.
Thoughts
Milestones
Our founders are Bakar Innovation Fellows
Oliver Sun and Eric Wang are Bakar Innovation Fellows at UC Berkeley.
Reasoned took part in Berkeley SkyDeck Pad-13
The team joined Berkeley SkyDeck's Pad-13 program, its track for biotech and life-science startups.
Supported by NVIDIA Inception, Google for Startups and Microsoft for Startups
Three startup programs support the compute behind AiMiner.
Reasoned Therapeutics is incorporated in Berkeley
The company is founded to build AiMiner: Discovery Intelligence for small-molecule drug hunting teams.
Papers
- KinConfBench
A Curated Benchmark for Cofolding Models on Kinase Conformational States
npj Drug Discovery
- SAGA
Accelerating Scientific Discovery with Autonomous Goal-evolving Agents
Nature Machine IntelligenceAccepted
- CAFE
- GeomLlama
- IDPForge
- LP-PDBBind
Leak Proof PDBBind: A Reorganized Data Set of Protein-Ligand Complexes for More Generalizable Binding Affinity Prediction
Journal of Physical Chemistry B
- LinkLlama
LinkLlama: Enabling Large Language Model for Chemically Reasonable Linker Design
Journal of Chemical Information and Modeling
- UCBBind
More Accurate Binding Affinity Prediction Using Protein Homology and Ligand-Based Transfer Learning
Journal of Chemical Information and Modeling
- SmileyLlama
SmileyLlama: modifying large language models for directed chemical space exploration
Nature Computational Science
- HiQBind
- Polaris
Polaris Challenge: Data-Driven Priors to Improve Docking for Pose Prediction
Journal of Chemical Information and Modeling
- SynLlama
- iMiner
Mining for Potent Inhibitors through Artificial Intelligence and Physics: A Unified Methodology for Ligand Based and Structure Based Drug Design
Journal of Chemical Information and Modeling
- MCSCE
